Assisted Reproductive Technologies and Infectious Diseases: by Andrea Borini, Maria Valeria Savasi

By Andrea Borini, Maria Valeria Savasi

This concise and sensible e-book is the 1st of its sort to envision using assisted reproductive applied sciences (ART) relating to blood-borne infectious illnesses: human immunodeficiency virus (HIV), hepatitis B (HBV) and hepatitis C (HCV). The booklet opens with a dialogue of the influence of those viruses on female and male fertility, by way of particular chapters of every of them, together with paintings with HIV and HCV serodiscordant couples (where both the male or woman is confident) and the detection and influence of HBV and HCV in human gametes and embryos. a massive personality on laboratory defense while appearing paintings with blood-borne viruses follows, and the e-book concludes with a dialogue of artwork in austere and resource-poor settings, the place those infections are frequently dominant as a result of loss of remedy and entry to vaccines. Written and edited through a world array of specialists in reproductive medicine, Assisted Reproductive applied sciences and Infectious Diseases explores questions, innovations, and similar concerns with the purpose of successfully supporting clinicians operating with serodiscordant wishing to have children. 

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In this study, a low serum testosterone level was described [102]. It is speculated that HCV might stimulate oxidative stress, which causes impaired spermatogenesis in general and impaired motility in particular. It is unknown whether or not antiviral therapy can undo these changes [102]. Therapy for HCV and Male Fertility Until a few years ago, ribavirin and peginterferon constituted the most effective treatment available for HCV, with a sustained response in 40–50 % of patients. Because of embryo toxicity and teratogenic effects described in animal studies, partners of men on Longitudinal cohort Durazzo et al.

5. Anderson DJ, et al. White blood cells and HIV-1 in semen from vasectomised seropositive men. Lancet. 1991;338(8766):573–4. 6. Nuovo GJ, et al. HIV-1 nucleic acids localize to the spermatogonia and their progeny. A study by polymerase chain reaction in situ hybridization. Am J Pathol. 1994;144(6):1142–8. 7. Bagasra O, et al. Detection of HIV-1 proviral DNA in sperm from HIV-1-infected men. AIDS. 1994;8(12):1669–74. 1 The Impact of Human Immunodeficiency Virus… 23 8. Scofield VL, et al. HIV interaction with sperm.

25. Ping LH, et al. Effects of genital tract inflammation on human immunodeficiency virus type 1 V3 populations in blood and semen. J Virol. 2000;74(19):8946–52. 26. Crittenden JA, Handelsman DJ, Stewart GJ. Semen analysis in human immunodeficiency virus infection. Fertil Steril. 1992;57(6):1294–9. 27. Krieger JN, et al. Fertility parameters in men infected with human immunodeficiency virus. J Infect Dis. 1991;164(3):464–9. 28. Muller CH, Coombs RW, Krieger JN. Effects of clinical stage and immunological status on semen analysis results in human immunodeficiency virus type 1-seropositive men.

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