By Daryl S. Paulson
From the slippery protecting on rocks in a circulate, to the clogging slime in a bath drain, biofilms are found in lifestyle in various types. This doubtless innocuous build-up additionally money owed for eighty percentage of all microbial infections. With chapters authored by way of skilled members from academia and undefined, Applied Biomedical Microbiology: A Biofilms method demonstrates powerful how you can wrestle the overall healthiness and fiscal havoc that biofilms are wreaking, whereas additionally tapping into their confident strength.
Replete with Tables and Illustrations, Many in Color
Under the editorial information of esteemed business microbiologist Dr. Daryl Paulson, this publication provides an in-depth dialogue of medically tough biofilms. It offers a fantastic starting place within the easy microbiology of biofilms after which is going directly to talk about the biofilms linked to scientific units, catheters, and dental unit water strains in addition to those who impression cardiovascular medication, the gastrointestinal method, periodontal ailment, and persistent wounds. This informative paintings concludes with an exploratory bankruptcy of some of the equipment used to enquire biofilms.
Applied Biomedical Microbiology: A Biofilms technique presents key info basically and concisely – an invaluable consultant for environmental, meals, and water microbiologists in addition to biochemists, pharmaceutical scientists, and product and biofilm engineers.
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Extra resources for Applied biomedical microbiology : a biofilms approach
A. Bacterial resistance to tetracycline: Mechanisms, transfer and clinical significance. Clin. Microbiol. Rev. 5, 387, 1992. 25. , et al. The maintenance in the oral cavity of children of tetracycline resistant bacteria and the genes encoding such resistance. J. Antimicrob. Chemother. 56, 524, 2005. 26. , et al. Prevalence and identification of tetracycline-resistant oral bacteria in children not receiving antibiotic therapy. FEMS Microbiol. Lett. 228, 99, 2003. 27. , et al. Prevalence, proportions, and identities of antibiotic-resistant bacteria in the oral microflora of healthy children.
This figure shows the movement of DNA by conjugation, mediated by plasmids and transposons, and transduction, mediated by bacteriophages and transformation of DNA derived from dead, lysed bacterial cells. Evidence for horizontal gene transfer of antibiotic resistance in the oral cavity Whole genome sequencing and the analysis of individual genes can tell us if particular genes are likely to have been acquired by horizontal transfer, as genes that are 95 to 100% identical in diverse bacteria (such as tet(M)) are highly likely to have been acquired in this way.
1% of the total cultivable flora, and that this elevated level of resistance was sustained for at least 8 weeks after treatment . This change in the antibiotic resistance profile of oral biofilms following exposure to antibiotics is important and will be considered in greater detail later in this chapter. As we have seen, many of these resistance genes are found on mobile elements that are capable of transferring from one bacterium to another. indb 31 8/28/09 6:25:04 PM 32 Applied biomedical microbiology: A biofilms approach environment.