By Thomas T. Yoshikawa, Shobita Rajagopalan
Written by way of the key professionals at the subject, this reference presents easy accessibility to crucial info on particular antibiotics, significant scientific infections, chosen pathogens, and infections in long term elderly-care facilities-summarizing the sizeable array of issues concerning infectious ailments in older adults together with epidemiology, medical manifestations, altered host resistance, and pharmacology.
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3. Altered Clinical Manifestations It has long been recognized that older persons commonly present with signiﬁcant infection in the absence of classic signs. Deﬁnitions used in infectious disease epidemiology change secondary to differences in disease presentation of the elderly, and therefore knowledge of age-speciﬁc differences in presentation is essential to avoid selection and misclassiﬁcation bias (17). Fever, the cardinal sign of infection, may be absent or blunted 20% to 30% of the time (18).